| 中文名称 |
4E-BP1 (Phospho 4E-BP1 (Phospho Thr37/46)) Rabbit mAb |
| 储存条件 |
-20°C/1 year |
| 基因名称 |
4E BP1 |
| 蛋白名称 |
Eukaryotic translation initiation factor 4E-binding protein 1 |
| 其他名称 |
EIF4EBP1;Eukaryotic translation initiation factor 4E-binding protein 1;4E-BP1;eIF4E-binding protein 1;Phosphorylated heat- and acid-stable protein regulated by insulin 1;PHAS-I |
| Gene Id |
1978 |
| Swissprot Number |
Q13541 |
| 宿主种属 |
Rabbit |
| 应用范围 |
WB,IP,ELISA |
| 稀释比例 |
WB 1:2000-1:10000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| 反应种属 |
Human,Mouse,Rat |
| 克隆性 |
Monoclonal |
| 特异性 |
endogenous |
| 同种型 |
Rabbit IgG |
| 保存液 |
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| 纯化方式 |
Protein A |
| 背景资料 |
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008], |
| 蛋白分子量 |
MW(Calculated):13kD;MW(Observed):15-20kD |
